In this talk we study an all-at-once linear system arising from the nonlinear tempered  diffusion equation with variable coefficients. Firstly, the nonlinear and linearized implicit schemes are proposed to approximate such the nonlinear equation with continuous/discontinuous coefficients. The stabilities and convergences of the two schemes are proved under several suitable assumptions, and numerical examples show that the convergence orders of these two schemes are $1$ in both time and space. Secondly, a nonlinear all-at-once system is derived based on the nonlinear implicit scheme, which may suitable for parallel computations. Numerical examples demonstrate that the proposed preconditioner is efficient.